There are clear links between schizophrenia spectrum disorders (SSDs ) and depressive and anxiety disorders, though the nature of the links remains unclear. This has important implications for psychiatric nosology, aetiology and treatment.

This talk will review the literature on the comorbidity of depression and anxiety symptoms/disorders and SSDs in terms of their prevalence rates in clinical and non-clinical populations, the temporal relationship of depressive and anxiety comorbidity to SSDs, and the effect of comorbidity on outcome. Treatment implications will also be covered, with particular emphasis on OCD and social anxiety disorder.